Systematic Review of the Effectiveness of Botulinum Toxin or Radiotherapy for Sialorrhea in Patients with Amyotrophic Lateral Sclerosis
نویسندگان
چکیده
منابع مشابه
Application of botulinum toxin to treat sialorrhea in amyotrophic lateral sclerosis patients: a literature review
Amyotrophic lateral sclerosis is a progressive and fatal neurodegenerative disease characterized by the degeneration of motor neurons, which are the central nervous system cells that control voluntary muscle movements. The excessive salivation (sialorrhea) is present in approximately 50% of amyotrophic lateral sclerosis cases. Thus, some alternative therapeutic methods are sought, such as antic...
متن کاملApplication of botulinum toxin to reduce the saliva in patients with amyotrophic lateral sclerosis.
AIM To demonstrate the effect of local application of Botox(R) in patients with amyotrophic lateral sclerosis (ALS), following our 2002 institutional protocol of sialorrhea treatment. STUDY DESIGN Clinical prospective. MATERIAL AND METHOD Five patients with ALS assisted at Clinic of Otolaryngology of AACD (Associação de Assistência à Criança Deficiente). They were all submitted to local app...
متن کاملEfficacy of transdermal scopolamine for sialorrhea in patients with amyotrophic lateral sclerosis
Background: Sialorrhea, the excessive flow of saliva from the mouth, causes distress in about half of patients with amyotrophic lateral sclerosis (ALS). Treatments of sialorrhea in ALS include systemic anticholinergic drugs, amitriptyline, botulinum toxin injection, and salivary gland radiotherapy, although each has limitations. Scopolamine transdermal patches have been used to prevent motion s...
متن کاملEvaluation of Pulmonary Function Test in Patients with Amyotrophic lateral sclerosis and its correlation with the symptoms of the disease
Introduction: Amyotrophic lateral sclerosis (ALS) is a neurogenic progressive disease that leads to muscle atrophy. The purpose of this study was to evaluate pulmonary function test (PFT) in patients with ALS and its correlation with ASL symptoms. Materials and Methods: This cross-sectional study was performed on 32 ALS patients at Ghaem Hospital, Mashhad...
متن کاملA review of options for treating sialorrhea in amyotrophic lateral sclerosis.
Sialorrhea or drooling represents quite a common problem in patients with amyotrophic lateral sclerosis (ALS). In this review, we describe the possible treatments for this issue. Current medical management is not always effective: anticholinergic drugs (atropine, glycopyrrolate, amitriptyline, hyoscyamine, and transdermal scopolamine) are often used, but there is very little evidence of their e...
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ژورنال
عنوان ژورنال: Journal of Pain and Symptom Management
سال: 2009
ISSN: 0885-3924
DOI: 10.1016/j.jpainsymman.2008.02.006